Van den Heuvel-Eibrink group
Prof. Van den Heuvel-Eibrink’s research-group is dedicated to translational research in pediatric oncology, with a special focus on renal rumors and the (genetic) variation of early and late toxicity of childhood cancer treatment including the long-term development of children prenatally exposed to maternal cancer (treatment) through (inter)national collaboration.
Contact
Marry van den Heuvel - Eibrink
Renal tumors
Research is focused on clinical outcome determinants for survival and toxicity after childhood renal cancer, including Wilms tumors, as well as rare non-Wilms tumors. The research projects aim for diagnostic innovation (radiology, diagnostic discriminating molecular biomarker identification), oncogenetic characterization (genotype-phenotype correlation and identification of renal tumor-susceptibility), molecular tumor characterization (NGS, organoids, and target identification, compound screens), and innovative treatment development (chemotherapy, immunotherapy, radiotherapy and surgical treatment).
“Our group is dedicated to translational research with a special focus on renal tumors and the (genetic) variation of early and late toxicity of childhood cancer through international collaboration.”
Marry van den Heuvel-Eibrink
Research group leader
Quality of cure and toxicity research
The group of Prof. Dr. van den Heuvel-Eibrink focus on the identification of (genetic) determinants of early and late toxicity of childhood cancer, especially endocrine sequelae, and ototoxicity. Research projects are specifically focused on frailty, osteoporosis, fertility and ototoxicity, including tinnitus and hearing loss. The study results contribute to development of international surveillance guideline and intervention studies. In addition to toxicity following childhood cancer, Prof. Dr. van den Heuvel-Eibrink is involved in the outpatient expertise center on Cancer In Pregnancy (CIP), aiming to develop clinical guidelines, so physicians can treat pregnant women with a cancer diagnosis more targeted, and reduce its possible effects on the child’s outcome.
Grants, awards and publications
Join us
To cure every child with cancer, we are looking for the best scientists! Working in a top organization demands highly qualified employees who perform to their utmost in a work environment with continuous motivation for improvement. Do you recognize yourself in our core values as groundbreaking and passionate? Explore the job opportunities in our research department.
Explore job opportunities